IgM (Immunoglobulin M)

Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to antigen.[1] The spleen is the major site of specific IgM production. [2]

IgM (Immunoglobulin M) antibody molecule consisting of 5 base units.
1: Base unit.
2: Heavy chains.
3: Light chains.
4: J chain.
5: Intermolecular disulfide bonds.

IgM scheme. Heavy chains are blue; light chains are yellow.

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