Slo Niacin Polygel Controlled-Release Niacin, 500 mg – 100 Tablets | Rite Aid

Product Details

SLO-NIACIN® dietary supplement tablets contain nicotinic acid which is clinically proven to support good cholesterol (HDL). SLO-NIACIN® Tablets can help maintain good cholesterol (HDL) within the normal range.1† The nicotinic acid in SLO-NIACIN® Tablets is a member of the vitamin B-complex group.

SLO-NIACIN® utilizes a distinctive polygel® controlled-release system that ensures the gradual and measured release of niacin. It is designed to reduce the incidence of flushing commonly associated with niacin use.1,2

A few great reasons to use SLO-NIACIN®:

The #1 preferred niacin supplement with nicotinic acid.1
Among the forms of niacin (including flush-free niacin: inositol hexaniacinate, inositol hexanicotinate, or nicotinamide) only nicotinic acid, the key ingredient in SLO-NIACIN®, is clinically proven to support good cholesterol (HDL).3
Contains a doctor-recommended form of niacin.
A top pharmacist-recommended brand.1
Leading cardiologist, Dr. Carl Lavie, Medical Director, Cardiac Rehabilitation and Prevention at the John Ochsner Heart and Vascular Institute, New Orleans, LA, urges people seeking dietary supplement niacin to make informed choices when adding one to their daily health routine because some of them have not been clinically proven to support good cholesterol.

Watch the video to learn more.

SLO-NIACIN® has been recommended and trusted by healthcare professionals for more than 25 years

Manufactured by Upsher-Smith Laboratories, Inc. – Partners in Health since 1919

Facts About Flushing

About Flushing
When taking niacin supplements, some people, but not all, may experience a side effect called niacin flushing. Niacin flushing may occur with the use of nicotinic acid, which causes temporary vasodilation or widening of blood vessels in the skin. Symptoms of niacin flushing may include temporary itching and tingling, feelings of warmth and headache, particularly when beginning or increasing the dose. SLO-NIACIN® contains nicotinic acid, but the distinctive polygel® controlled-release system is designed to help reduce the likelihood of niacin flushing.2 It’s important to know that niacin flushing is usually temporary and seldom requires one to stop taking niacin.

SLO-NIACIN® is designed to minimize flushing
To help reduce the likelihood of niacin flushing, SLO-NIACIN® Tablets have been designed with a distinctive polygel® controlled-release system that ensures the gradual and measured release of nicotinic acid into the body.1 Controlled release of nicotinic acid is intended to minimize flushing and itching while ensuring that you receive a doctor-recommended form of niacin trusted to help support good cholesterol levels (HDL).1

The “flush-free” myth
Although “flush-free” types of niacin (inositol hexaniacinate, inositol hexanicotinate, or nicotinamide) may not cause flushing, these types of niacin are not clinically proven to support good cholesterol.3 Some even recommend against “flush-free” types of niacin because they are not clinically proven to support good cholesterol.3

Tips to avoid niacin flushing1

Talk to your healthcare professional about taking 1 aspirin or ibuprofen 30 minutes before taking SLO-NIACIN® Tablets
Take SLO-NIACIN® Tablets with a low-fat snack and cold water
Take SLO-NIACIN® Tablets before going to bed
Do not take SLO-NIACIN® Tablets with spicy foods, alcohol, coffee, tea, or other hot drinks


Is the nicotinic acid in SLO-NIACIN® natural?
The niacin, or nicotinic acid, used in SLO-NIACIN® is chemically synthesized. However, niacin is a naturally occurring B vitamin that aids in the function of the digestive system, skin, and nervous system.

Can the SLO-NIACIN® Tablet pass through the body intact and appear in the stool?
It is not expected for persons taking SLO-NIACIN®, who experience regular bowel movements daily or less frequently, to pass an intact SLO-NIACIN® Tablet or a fragment of a tablet in the stool. However, occasionally a fragment of a tablet may be seen in the stool if a person has more frequent stools. If a tablet fragment is excreted intact, the user may not have received the full amount of niacin contained within the tablet.


Niacin may cause temporary flushing, itching and tingling, feelings of warmth and headache, particularly when beginning, increasing amount or changing brand of niacin. These effects seldom require discontinuing niacin use. Skin rash, upset stomach, and low blood pressure when standing are less common symptoms; if they persist, contact a physician.

SLO-NIACIN® Tablets should not be used by persons with a known sensitivity or allergy to niacin. Persons with heart disease, particularly those who have recurrent chest pain (angina) or who recently suffered a heart attack, should take niacin only under the supervision of a physician. Persons taking high blood pressure or cholesterol-lowering drugs should contact a physician before taking niacin because of possible interactions. Case reports of myopathy (unexplained muscle related complaints, including discomfort, weakness, or tenderness) have been documented with the use of HMG-CoA Reductase Inhibitors in combination with lipid-altering doses of niacin therapy (≥1 gram of niacin per day). Do not take niacin unless recommended by and taken under the supervision of a physician if you have any of the following conditions: gallbladder disease, gout, arterial bleeding, glaucoma, diabetes, impaired liver function, peptic ulcer, pregnancy or lactating women. Increased uric acid and glucose levels and abnormal liver function tests have been reported in persons taking daily doses of 500 mg or more of niacin.
Discontinue use and consult a physician immediately if any of the following symptoms occur: persistent flu-like symptoms (nausea, vomiting, a general “not well” feeling); loss of appetite; a decrease in urine output associated with dark-colored urine; muscle discomfort such as tender, swollen muscles or muscle weakness; irregular heartbeat; or cloudy or blurry vision.
Keep out of reach of children.

  1. Data on file. Upsher-Smith Laboratories, Inc. 2016.
  2. Slo-Niacin [product information]. Maple Grove, MN: Upsher-Smith Laboratoories Inc.: 2015.
  3. More on niacin: No flush, no good. Harvard Health Lett. 2007;July:7.

At Rite Aid, we provide you with the support, products, pharmacy services, and the wellness+ rewards savings opportunities you need to keep your whole family healthy. With us, it’s personal.

Call Us Chat With us Leave us Feedback Facebook Twitter Youtube
About Us

Customer Care

Online Shop

Site Help

Corporate Info

Legal Information

dot pharmacy verified. What does it mean to be a pharmacy-verified website? Find out at
© 2001-2018 Rite Aid Corp. All rights reserved.

Leave a Reply: (What... You're shy?)

Please log in using one of these methods to post your comment: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s