Tag Archives: Antiretroviral drug

This Day in the Yesteryear: US APPROVES ANTIRETROVIRAL DRUG AZT AS A TREATMENT FOR AIDS (1987)


US Approves Antiretroviral Drug AZT as a Treatment for AIDS (1987)

Though it was originally developed as an anticancer drug in 1964, azidothymidine (AZT) was never approved for that purpose. Two decades later, however, it was discovered to be effective in fighting HIV. At the time, thousands of people were dying of AIDS, and no other treatment was forthcoming. For humanitarian reasons, the drug was approved by the US Food and Drug Administration in a matter of months, rather than the usual eight to 10 years. How does the drug prevent HIV from reproducing? More… Discuss

Gamers Help AIDS Researchers Solve Enzyme Puzzle


Gamers Help AIDS Researchers Solve Enzyme Puzzle

In just weeks, online gamers were able to solve a puzzle that has stumped AIDS researchers for years. They did so using a game called Foldit, which allows players to compete against one another to, among other things, predict a protein‘s optimal—or most stable—three-dimensional structure. In this case, players were presented with M-PMV retroviral protease, an enzyme that is critical to the development of a virus similar to HIV. The protein model that the gamers came up with could help scientists develop better AIDS drugs. More… Discuss