Tag Archives: Cancer

Health- BBC: A dog has been used to sniff out thyroid cancer in people who had not yet been diagnosed, US researchers say.


Frankie the dogA dog has been used to sniff out thyroid cancer in people who had not yet been diagnosed, US researchers say.

Tests on 34 patients showed an 88% success rate in finding tumours.

The team, presenting their findings at the annual meeting of the Endocrine Society, said the animal had an “unbelievable” sense of smell.

Cancer Research UK said using dogs would be impractical, but discovering the chemicals the dogs can smell could lead to new tests.

The thyroid is a gland in the neck that produces hormones to regulate metabolism.

Thyroid tumours are relatively rare and are normally diagnosed by testing hormone levels in the blood and by using a needle to extract cells for testing.

Smelly jobCancers are defective, out-of-control cells. They have their own unique chemistry and release “volatile organic compounds” into the body.

The canine approach relies on dogs having 10 times the number of smell receptors as people and being able to pick out the unique smells being released by cancers.

The man’s best friend approach has already produced promising results in patients with bowel and lung cancers.

A team at the University of Arkansas for Medical Sciences (UAMS) had previously showed that a dog could be trained to smell the difference between urine samples of patients with and without thyroid cancer.

Frankie the dogFrankie gave the correct diagnosis in 30 out of 34 cases

The next step was to see if it could be used as a diagnostic test.

Frankie the German Shepherd was trained to lie down when he could smell thyroid cancer in a sample and turn away if the urine was clean.

Thirty-four patients, who were going to hospital for conventional testing, took part in the trial.

Frankie gave the correct diagnosis in 30 out of 34 cases. There were two false positives and two patients who would have been incorrectly given the all-clear.

Dr Donald Bodenner, the chief of endocrine oncology at UAMS, said: “The capability of dogs to smell minute amounts is unbelievable.

“The medical community over the next few years is going to have a great appreciation [for them].

E-noseSome researchers are trying to strip out the canine-element and test for the unique pong of cancer with an “electronic nose”.

This approach is also being trailed outside of cancer and has been used to find dangerous infections such as Clostridium difficile.

Dr Bodenner added: “We would like to know what Frankie is smelling, nobody knows.”

Commenting on the findings Dr Jason Wexler, an endocrinologist in Washington, DC, argued: “This is a fascinating, interesting study and it has high potential in areas of the world that may not have access to biopsy techniques.

“There are many patients who are reluctant to undergo fine needle aspiration so I think that if you could design a technique where you have no invasive procedure that can have tremendous widespread appeal.”

But Dr Emma Smith, from Cancer Research UK, cautioned: “Although there’s some evidence that some trained dogs can sniff out the smelly molecules given off by cancers, there have been mixed results on how accurate they are and it’s not really practical to think about using dogs on a wide scale to detect the disease.

“But carrying out lab tests to understand what the dogs are smelling might help to inform the development of ‘electronic noses’ to detect the same molecules, which could lead to better diagnostic tests in the future.”

Dr Bodenner says it is an approach that he is actively pursuing.

Meanwhile, the lab is also trying to find a new home for canine-veterans from Iraq and Afghanistan.

Instead of sniffing out bombs, they will be trained to hunt for cancer.

line

Symptoms of thyroid cancer

  • A painless lump or swelling at the front of the neck below the Adam’s apple
  • Unexplained hoarseness that doesn’t get better after a few weeks
  • Sore throat or difficulty swallowing that doesn’t get better
  • Pain in the neck

Source: NHS Choices

line

More on This Story

Related Stories

The BBC is not responsible for the content of external Internet sites

More videos from the BBC

More Health stories

RSS

Features & Analysis

BBC Future

Knowing how to trigger an immune response may help beat cancer (SPL)

Can we make the body self-heal?

Lessons from baffling cancer ‘miracles’ Read more…

Programmes

  • Google's Street View (Trekker) camera on a zip wire in the Amazon rainforest Click Watch

    Google sends a camera through the Amazon rainforest on a zip wire, plus other tech news

BBC News Daily Newsletter

newsletter signupToday’s breaking news
and more in your inbox

Sign up now

Ads by Google

Advertisements

*Breathing Techniques* (Yoga, Meditation, Relaxation, Stress, Cancer, Blood Pressure) Kapalbhati


*Breathing Techniques* (Yoga, Meditation, Relaxation, Stress, Cancer, Blood Pressure) Kapalbhati

this pressed for your awareness: 10 Household Products That Have KILLED People – Likes


10 Household Products That Have KILLED People – Likes.

Visit, subscribe, enjoy: Valentina Lisitsa, Pianist on YouTube


Valentina Lisitsa pianist visit her YouTube Channel

Valentina Lisitsa pianist visit her YouTube Channel (Click to access YouTube Channel)

A great cartoon by @varvel just now — Arnold Melm (@countUP)


#JeSuisCharlie, one of the most popular hashtags ever, was in 3.4 million tweets in 24 hours — Conrad Hackett (@conradhackett)


Ibuprofen as Skin Cancer Prevention?


Ibuprofen as Skin Cancer Prevention?

The use of over-the-counter painkillers may lower one’s risk of squamous cell skin cancer—typically caused by sun exposure—by 15 percent, according to a new study. Researchers suspect that Ibuprofen and naproxen—the active ingredients found in the popular drugs Advil, Motrin, and Aleve—disrupt the proteins in the body that contribute to cancerous tumors. The scientists caution that more research is necessary, since painkillers carry their own risks. More… Discuss

from http://www.ehealthme.com/ds/ibuprofen/multiple+myeloma:

Summary: Multiple myeloma is found among people who take Ibuprofen, especially for people who are male, 60+ old, have been taking the drug for < 1 month, also take medication Zometa, and have Multiple myeloma.

We study 57,989 people who have side effects while taking Ibuprofen from FDA and social media. Among them, 171 have Multiple myeloma. Find out below who they are, when they have Multiple myeloma and more.

You are not alone: join a mobile support group for people who take Ibuprofen and have Multiple myeloma >>>

From the BBC: Life choices ‘behind many cancers’


Life choices ‘behind more than four in 10 cancers’

unhealthy habits

Related Stories

More than four in 10 cancers – 600,000 in the UK alone – could be prevented if people led healthier lives, say experts.

Latest figures from Cancer Research UK show smoking is the biggest avoidable risk factor, followed by unhealthy diets.

The charity is urging people to consider their health when making New Year resolutions.

Life choices ‘behind many cancers’ http://www.bbc.co.uk/news/health-30589712

today’s holiday: St. Thorlak’s Day (2014)


St. Thorlak’s Day (2014)

Thorlak Thorhalli (1133-1193) was born in Iceland and, after being educated abroad, returned there to become bishop of Skalholt in 1177 or 1178. He was canonized by the Icelandic parliament five years after his death. His day traditionally marks the climax of Christmas preparations for Icelanders. It is associated with housecleaning, as well as the preparation of special foods. The hangiket, or smoked mutton, for Christmas was usually cooked on this day, and, in the western fjords, the smell of skate hash cooked on St. Thorlak’s Day is still considered a harbinger of the holiday season. More… Discuss

this pressed for hope: Immune system reboot takes center stage | MLive.com


Sue-IMG_3013.JPG

Mlive.com file| photoSue Schroder

First, a word about what we have and who we are from the Leukemia and Lymphoma Society, www.lls.org and the National Cancer Institute’s Cancer Statistics Review:

Leukemia, lymphoma, myeloma and myelodysplastic syndrome (MDS) are types of cancer that can affect the bone marrow, the blood cells, the lymph nodes and other parts of the lymphatic system. Each is likely a result of changes to the DNA of a single stem cell.

By the numbers:

* Leukemia, lymphoma and myeloma are expected to account for 9.4 percent of the estimated 1.6-plus million new cancer cases diagnosed in the U.S. this year;

An estimated 1.3 million in the U.S. are living with, or are in remission from, leukemia, Hodgkin lymphoma, non-Hodgkin lymphoma or myeloma.

The immune system is at the center of one area of change.

A major reason blood cancers develop is a failure of the immune system to recognize malignant cells, Brinker said.

He talked about a study of Chimeric Antigen Receptor technology (CAR), at the University of Pennsylvania:

“B-cells are the bad cells in B-lymphocyte leukemias and lymphomas, which are the majority of non-Hodgkin lymphomas and lymphocytic leukemias.

“T-cells are like the military police, they regulate the B-cells.” In some lymphomas and leukemia, malfunctioning T-cells are the evildoers.

“We can put a virus into T-cells in a Petri dish and get them supercharged to specifically fight B-lymphocytes.

“The T-cells are then stimulated to reproduce,” and an army of killer T-cells is re-introduced into the body to destroy the cancer and stick around to take out new threats.

Via Immune system reboot takes center stage | MLive.com

http://www.mlive.com/health/index.ssf/2014/12/immune_system_reboot_takes_cen.html

let’s not forget: Smallpox (1908). Eradicated thanks to marvels of vaccinations — Lindsey Fitzharris (@DrLindseyFitz)


Take a Break from Taking a Load Off ( in order to keep our old memories alive we need to create new ones)


Take a Break from Taking a Load Off

It has been well documented that physical activity is vital to maintaining one’s health. While moderate to vigorous exercise provides the greatest benefit, even simply shifting from a sitting to a standing position could greatly benefit older adults. Researchers found that highly sedentary older adults who repeatedly break-up their sedentary behavior throughout the day have higher physical function than those who do not. They therefore recommend that for every hour spent in sedentary behavior, older adults interrupt it nine times. More… Discuss

New Multiple Myeloma Drug Set to Begin Clinical Trials|Specialty Pharmacy TIme


Specialty Pharmacy News

Treatment inhibits key process that enables cancer cells to multiply.

Researchers in London plan to begin clinical trials on a significant new treatment for multiple myeloma by the end of next year.

In laboratory testing, the drug, known as DTP3, killed myeloma cells within human cells and mice without causing any toxic side effects. In a paper published on October 13, 2014 in Cancer Cells, researchers outlined how the drug inhibits a key process that allows cancer cells to multiply.

“Lab studies suggest that DTP3 could have therapeutic benefit for patients with multiple myeloma and potentially several other types of cancer, but we will need to confirm this in our clinical trials, the first of which will start next year,” said lead researcher Professor Guido Franzoso in a press release.

DTP3 was developed through an evaluation of the mechanisms that enable cancer cells to continue multiplying beyond their normal lifespan. Specifically, the researchers studied a protein called nuclear factor kappa B (NF-kB), which plays a key role in inflammation, in addition to immune and stress response systems.

“We had known for many years that NF-kB is very important for cancer cells, but because it is also needed by healthy cells, we did not know how to block it specifically,” Franzoso said. “The discovery that blocking the GADD45β/MKK7 segment of the NF-κB pathway with our DTP3 peptide therapeutic selectively kills myeloma cells could offer a completely new approach to treating patients with certain cancers, such as multiple myeloma.” – See more at: http://www.specialtypharmacytimes.com/news/New-Multiple-Myeloma-Drug-Set-to-Begin-Clinical-Trials#sthash.XGAUTmks.Gyz2Cy02.dpuf

via New Multiple Myeloma Drug Set to Begin Clinical Trials.

Seattle Genetics: Blood Cancer Awareness Month


Seattle Genetics: Blood Cancer Awareness Month.

Gold as Cancer Fighter


Gold as Cancer Fighter

Alternative medicine proponents have long attributed healing properties to gold, and in recent years, mainstream medical researchers have begun looking to the precious metal as well. In a recent study, tiny gold particles encased in the chemotherapy drug cisplatin appeared to boost the effectiveness of conventional radiotherapy and chemotherapy treatment for an aggressive brain cancer. Cancer cells in samples subjected to this experimental treatment were completely eradicated, and over the next 20 days there was no regrowth. More… Discuss

this pressed-from Science Friday: Giving Viruses a License to Kill…Cancer


Giving Viruses a License to Kill…Cancer.

Giving Viruses a License to Kill…Cancer The lab of Dr. Mark Federspiel at the Mayo Clinic, where the measles virus is being grown in bioreactors for the next clinical trial coming up in September. Photo by Mayo Clinic

just a thought: What good is an idea, if it survives its last brain that contemplatedit?


just a thought: “What good is an idea, if it survives its last brain that contemplated it?”
(George B ©always)

this pressed: Multiple Myeloma: International Myeloma Foundation : • health professionals : imwg conference series : The IMWG Conference Series “Making Sense of Treatment” June 11, 2014


 

Multiple Myeloma: International Myeloma Foundation : • health professionals : imwg conference series : The IMWG Conference Series “Making Sense of Treatment” June 11, 2014.

Enhanced by Zemanta

news: Cancer in Refugee Camps


Cancer in Refugee Camps

Historically, combating infectious diseases and malnutrition have been the primary concerns of health workers in refugee camps. Unfortunately, this leaves those refugees with equally deadly but non-communicative and expensive-to-treat diseases, like cancer, with few treatment options. This is a growing problem, say researchers, as refugees today remain displaced for substantially longer periods than in the past and the numbers of those displaced have swelled considerably in recent years. Between 2010 and 2012, the UNHCR Exceptional Care Committee, which funds costly medical care for refugees, approved and funded just half of the applications from refugees in Jordan with cancer. More… Discuss

Enhanced by Zemanta

7 buruieni numai bune de inclus în meniu – Yahoo Ştiri România


7 buruieni numai bune de inclus în meniu – Yahoo Ştiri România.

Plantain. In childhood, we treat abrasions, scratches and bruises plantain leaves freshly picked. This plant can be used in the kitchen but in salads, stews and soups. However, in addition to leaves, inflorescence and seeds are edible. Seeds, dried and ground are a rich source of fiber and are effective in the treatment of constipation. “

Enhanced by Zemanta

news: Measles Virus Used to Wipe Out Cancer (multiple myeloma)


Measles Virus Used to Wipe Out Cancer

Researchers are cautiously optimistic about an experimental cancer treatment that uses a modified measles virus to target and kill cancerous cells. Two out of six multiple myeloma patients who were treated with extremely high doses of the engineered viruses responded to the treatment, with one appearing to enter into complete remission. These two patients were found to have few or no circulating measles antibodies, important because this affords the virus a chance to attack the cancer cells before the patient’s immune system begins fighting off the virus. More… Discuss

Enhanced by Zemanta

10-Year Cancer Survival Up in England and Wales


10-Year Cancer Survival Up in England and Wales

Better diagnostic tools as well as treatments are helping cancer patients live longer in England and Wales. Half of people now being diagnosed with cancer there will survive for at least a decade, double the rate of the early 1970s. However, for some cancers, like pancreatic cancer and lung cancer, survival rates remain extremely low. London-based Cancer Research UK lauded the progress but said that further inroads need to be made and set a goal of 75 percent 10-year survival within two decades. More… Discuss

Enhanced by Zemanta

Pomalidomide for Multiple Myeloma – National Cancer Institute


Pomalidomide for Multiple Myeloma – National Cancer Institute.

 

Otto Kahler

Otto Kahler (Photo credit: Wikipedia)

 

 

 

Multiple myeloma
Classification and external resources
Plasmacytoma ultramini1.jpg

Micrograph of a plasmacytoma, the histologiccorrelate of multiple myeloma. H&E stain
ICD10 C90.0
ICD9 203.0
ICD-O: M9732/3
OMIM 254500
DiseasesDB 8628
MedlinePlus 000583
eMedicine med/1521
MeSH D009101

 

Pomalidomide
Pomalidomide2DACS.svg
Systematic (IUPAC) name
4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Clinical data
Trade names Imnovid, Pomalyst
Licence data EMA:LinkUS FDA:link
Pregnancy cat. (US)
Legal status POM (UK) -only (US)
Routes Oral
Pharmacokinetic data
Protein binding 12–44%
Metabolism Hepatic (mostly CYP1A2 andCYP3A4 mediated; some minor contributions by CYP2C19 andCYP2D6)
Half-life 7.5 hours
Excretion Urine (73%), faeces (15%)
Identifiers
CAS number 19171-19-8 Yes
ATC code L04AX06
PubChem CID 134780
ChemSpider 118785 
UNII D2UX06XLB5 
ChEMBL CHEMBL43452 
Chemical data
Formula C13H11N3O4 
Mol. mass 273.24 g/mol

 

 

 

 

Enhanced by Zemanta

VITAMIN C POSSIBLE CANCER FIGHTER


Vitamin C Possible Cancer Fighter

In the 1970s, Nobel Prize – winning chemist Linus Pauling reported success treating cancer with intravenous vitamin C. However, when clinical trials of oral vitamin C failed to yield results, the medical establishment largely abandoned this line of research. Now, decades later, researchers are finding that injected vitamin C can kill cancer cells without harming healthy cells and that, when used in combination with chemotherapy, it can slow tumor growth and curb chemotherapy side effects. More… Discuss

 

Enhanced by Zemanta

NEWS: MUSIC VIDEO PROJECTS HELP YOUNG CANCER PATIENTS COPE


Music Video Projects Help Young Cancer Patients Cope

For most young people, writing a song and recording amusic video is mere fun, but for those battling cancer, it can prove therapeutic. Young cancer patients who worked with music therapists to write their own songs and then record them reported feeling more social support than those who simply listened toaudiobooks. They also coped with their cancer in more positive ways. Having cancer can be a socially isolating experience, but the process of expressing one’s feelings through music and video seems to improve patients’ outlook and make them feel more supported by family, friends, and medical professionalsMore… Discuss

 

Enhanced by Zemanta

NANOBODIES


Nanobodies

In the 1980s, research on monoclonal antibodiesantibodies mass produced in a laboratory to target a single antigen—generated excitement for their potential applications in fighting disease, especially cancer. However, their effectiveness in disease treatment has been limited. Today, a much smaller type of monoclonal antibody called a nanobody is being researched to treat diseases such as cancer and Alzheimer’s. Nanobodies were discovered during unrelated research on what animal? More… Discuss

 

DEPRESSION LARGELY UNTREATED IN HEAD AND NECK CANCER SURVIVORS


Depression Largely Untreated in Head and Neck Cancer Survivors

Cancer’s emotional toll does not always end when the disease is eradicated. Survivors of head and neck cancer in particular are at elevated risk for depression. This is not surprising, considering that treatments for these cancers often have physical side effects that lead to trouble swallowing and speaking and increase social isolation. Still, few actually seek treatment for their depression, and their risk of suicide is four times that of the general population. More… Discuss

 

“CANCER” IMPACTS PATIENTS’ TREATMENT PREFERENCES


“Cancer” Impacts Patients’ Treatment Preferences

The terminology a doctor uses when breaking the news of a diagnosis to a patient could affect which course of treatment the patient opts for. Women are more likely to choose surgery to treat ductal carcinoma in situ, a non-invasive type of breast lesion, when the word cancer is used in its description. When it is presented to them as “a breast lesion” or “abnormal cells,” as opposed to “non-invasive breast cancer,” they are more open to alternative treatment options like drugs and watchful waitingMore… Discuss

 

Peril in the West: Erionite


Officials Ponder Action on Cancer-Causing Erionite_FairWarning
Officials Ponder Action on Cancer-Causing Erionite_FairWarning (click on picture to continue reading the article)

Mesothelioma, an exceedingly rare and lethal form of cancer, was once thought to be caused only by inhaling asbestos fibers.

Then in the late 1970s, when astonishing rates of the disease were reported among villagers in central Turkey, it turned out that a different fibrous mineral was the culprit. Erionite was abundant in native soil and stone, and so easy to work with that villagers had used it to build homes.

In the most devastated communities, known locally as “cancer villages,” mesothelioma rates were off the charts — responsible for 40 percent to 50 percent of all deaths. Animal studies showed erionite to be 100 to 800 times more carcinogenic than asbestos and, according to a scientific paper, “almost certainly the most toxic naturally occurring fibrous mineral known.”

EGAH-Dogan-Re-evaluation

Cancer Costs Becoming Unsustainable


Cancer Costs Becoming Unsustainable

About 12 million people are diagnosed with cancer each year, and that number is expected to more than double over the next two decades. At the same time, cancer treatment costs are rapidly rising, meaning cancer care is quickly becoming unaffordable in many developed countries. According to a recent report published by a team of international experts, most treatments have a substantial cost but a limited benefit. As such, they are calling upon policy-makers, doctors, patients groups, and the health industry to come together to find ways to mitigate the financial burden of cancer treatment. More… Discuss

Formaldehyde the substance that kills the living and preserves the dead


Formaldehyde the substance that kills living and preserves the dead

Formaldehyde the substance that kills living and preserves the dead

Cancer Death Risk Greater for Men


Cancer Death Risk Greater for Men

US researchers say men diagnosed with cancer are more likely to die from the disease than women. They attribute the discrepancy in part to the fact that men are at greater risk of developing cancer than women, perhaps as a result of differences in exposure to carcinogens or hormonal or metabolic differences. According to the American Cancer Society, men have about a 1 in 2 chance of developing cancer, while women have just a 1 in 3 chance. In addition, men are more likely than women to have advanced disease by the time their cancer is detected. More… Discuss

WHO Labels Cell Phones “Possibly Carcinogenic”


WHO Labels Cell Phones “Possibly Carcinogenic”

After reviewing epidemiological studies relating to mobile phone use and to exposure to elec tromagnetic fields in the workplace, the World Health Organization‘s International Agency for Research on Cancer has concluded that current evidence does not establish a strong link between cell phone use and increased risk of a malignant type of brain cancer. However, it also does not rule it out. It has therefore classified the devices as “possibly carcinogenic” and recommends that, until additional research into the long-term effects of heavy mobile phone use provides more definitive data, consumers consider reducing their exposure. More… Discuss

Story Of Courage and Hope: Elisa And Nathan Bond


What makes us human? Is it the instinct of survival only, or is there much more than that? Is compassion for the suffering of others more important than our own life experience? When we need help, is anybody there to offer a helping hand, or will they take advantage of tha moment of weakness to distance themselves from you? Are our expectations from people we think we know more than they are ready and able to give? To Give: four letter word that carries so much power, is one of the most important verbs in human life. It has so many meanings, it is used so widely one can only imagine the meanings of the word: Please check the dictionary if you think that I exaggerate:
1. To make a present of: We gave her flowers for her birthday.
 (source: http://www.thefreedictionary.com/give)  
Some cultures still don’t have the notion of to have, having, owning: For them to give is still the verb to describe sharing with the community, as giving is all they own.

The story of this family made me think more about the courage it takes being a human, with responsibilities to others, important enough to ask for understanding and help when everything seems hopelessly  terminal.

 

Please contact the following site, to find out more about them:

Thank You!

Green Tea, effective in prostate cancer protection


This slideshow requires JavaScript.


According to the studies, it is clear that among other types of cancer, green tea effectively protects the male’s prostate health: What does that have to do with my posting? Well I do believe too that green tea is a clear health promoter, when served daily. I do not have a vested commercial interest in promoting it, but I would feel selfish at the least, not to publicly acclaim the many health benefits  experienced from green tea consumption:

Goodbye Coffee, Hello Green Tea!


Please read the article linked here for more information on recognized health benefits:http://en.wikipedia.org/wiki/Green_tea,

give it a try yourself: Don’t make it a New year resolution and waste 350 days…
start today instead: Make the next cup of your beverage  a cupful of green tea!