Tag Archives: Cell biology

health: One Kiss Carries 80 Million Bacteria


One Kiss Carries 80 Million Bacteria

This latest research may make you think twice before locking lips with anyone. The mouth is home to tens of millions of bacteria, and just one 10-second kiss can transfer as many as 80 million of them. The good news, if you want to call it that, is that while bacteria in the saliva seem to change quickly following a kiss, populations on the tongue remain more stable. This finding is important to researchers, as it could help with the development of bacterial therapies and treatments. More… Discuss

New Multiple Myeloma Drug Set to Begin Clinical Trials|Specialty Pharmacy TIme


Specialty Pharmacy News

Treatment inhibits key process that enables cancer cells to multiply.

Researchers in London plan to begin clinical trials on a significant new treatment for multiple myeloma by the end of next year.

In laboratory testing, the drug, known as DTP3, killed myeloma cells within human cells and mice without causing any toxic side effects. In a paper published on October 13, 2014 in Cancer Cells, researchers outlined how the drug inhibits a key process that allows cancer cells to multiply.

“Lab studies suggest that DTP3 could have therapeutic benefit for patients with multiple myeloma and potentially several other types of cancer, but we will need to confirm this in our clinical trials, the first of which will start next year,” said lead researcher Professor Guido Franzoso in a press release.

DTP3 was developed through an evaluation of the mechanisms that enable cancer cells to continue multiplying beyond their normal lifespan. Specifically, the researchers studied a protein called nuclear factor kappa B (NF-kB), which plays a key role in inflammation, in addition to immune and stress response systems.

“We had known for many years that NF-kB is very important for cancer cells, but because it is also needed by healthy cells, we did not know how to block it specifically,” Franzoso said. “The discovery that blocking the GADD45β/MKK7 segment of the NF-κB pathway with our DTP3 peptide therapeutic selectively kills myeloma cells could offer a completely new approach to treating patients with certain cancers, such as multiple myeloma.” – See more at: http://www.specialtypharmacytimes.com/news/New-Multiple-Myeloma-Drug-Set-to-Begin-Clinical-Trials#sthash.XGAUTmks.Gyz2Cy02.dpuf

via New Multiple Myeloma Drug Set to Begin Clinical Trials.


Stem Cells Created from Adults’ Cells

For the first time, researchers have successfullycreated stem cells from the skin cells of adults. This is considered the first step in developing patient-specific cells lines to treat diseases like heart failure, Parkinson’s, multiple sclerosis, and vision loss, but it is also the first step inhuman reproductive cloning, an issue fraught with ethical dilemmas. To create the stem cells, researchers fused a grown skin cell with an ovum whose DNA had been removed. The resulting embryo contains an inner lining of pluripotent stem cells. Of 39 attempts to create stem cells from adult cells, the researchers succeeded only once for each of their two skin cell donors. More… Discuss

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Today’s Birthday (July 7,): Camillo Golgi (1843)


Camillo Golgi (1843)

An Italian physician and cytologist, Golgi devised a way to stain nerve tissue and, using the technique, was able to clearly observe a neuron, now called a Golgi cell, along with its axon and dendrites branching off. The discovery led to the identification of the neuron as the basic structural unit of the nervous system. He also discovered the Golgi tendon organ and the Golgi apparatus. He shared the 1906 Nobel Prize with Santiago Ramón y Cajal. What discovery did Golgi make about malaria? More… Discuss