Tag Archives: Pomalidomide

Pomalidomide for Multiple Myeloma – National Cancer Institute


Pomalidomide for Multiple Myeloma – National Cancer Institute.

 

Otto Kahler

Otto Kahler (Photo credit: Wikipedia)

 

 

 

Multiple myeloma
Classification and external resources
Plasmacytoma ultramini1.jpg

Micrograph of a plasmacytoma, the histologiccorrelate of multiple myeloma. H&E stain
ICD10 C90.0
ICD9 203.0
ICD-O: M9732/3
OMIM 254500
DiseasesDB 8628
MedlinePlus 000583
eMedicine med/1521
MeSH D009101

 

Pomalidomide
Pomalidomide2DACS.svg
Systematic (IUPAC) name
4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Clinical data
Trade names Imnovid, Pomalyst
Licence data EMA:LinkUS FDA:link
Pregnancy cat. (US)
Legal status POM (UK) -only (US)
Routes Oral
Pharmacokinetic data
Protein binding 12–44%
Metabolism Hepatic (mostly CYP1A2 andCYP3A4 mediated; some minor contributions by CYP2C19 andCYP2D6)
Half-life 7.5 hours
Excretion Urine (73%), faeces (15%)
Identifiers
CAS number 19171-19-8 Yes
ATC code L04AX06
PubChem CID 134780
ChemSpider 118785 
UNII D2UX06XLB5 
ChEMBL CHEMBL43452 
Chemical data
Formula C13H11N3O4 
Mol. mass 273.24 g/mol

 

 

 

 

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